Inter MilanNapoliSoccerSerie A

Serie A Title Showdown: Inter vs. Napoli – Predicted Lineups, Team News & Betting Odds

The summit of Italian football takes center stage at the San Siro this Sunday as league leaders Inter Milan host defending champions Napoli. In a clash that could define the 2025/26 Scudetto race, Cristian Chivu looks to cement his legacy in his first full season as Nerazzurri boss against his predecessor and tactical mastermind, Antonio Conte.

With Inter currently holding a four-point lead over the third-placed Partenopei, the pressure is at an all-time high in Milan.


Match Information: Inter vs. Napoli

EventSerie A – Matchday 20
DateSunday, January 11, 2026
Kick-off Time20:45 CET / 14:45 ET
VenueSan Siro (Giuseppe Meazza), Milan
RefereeDaniele Doveri
Where to Watch > 📺DAZN (Italy), Paramount+ (USA), TNT Sports (UK)

The Form Guide

Inter Milan: Under Cristian Chivu, the Nerazzurri are on a blistering six-game winning streak in the league. Their midweek 2-0 victory over Parma showcased a team in peak physical condition, led by the clinical Lautaro Martinez and the creative engine of Federico Dimarco.

Napoli: Despite being the reigning champions, Conte’s side has stumbled recently, dropping points in a 2-2 draw with Hellas Verona. However, they remain the most resilient defensive unit in the league.

Lautaro Martinez of Inter of Milan during the UEFA Champions League group F match between Inter and FC Barcelona at Giuseppe Meazza Stadium on December 10, 2019 in Milan, Italy.
(Photo by Jose Breton/Pics Action/NurPhoto via Getty Images)

Team News & Injury Updates

Inter Milan:

  • Denzel Dumfries: Out (Ankle surgery, expected return March).
  • Davide Frattesi: Doubtful (Muscle fatigue).
  • Hakan Calhanoglu: Fully recovered and set to pull the strings in midfield.

Napoli:

  • Kevin De Bruyne: Out (High-grade thigh tear).
  • Romelu Lukaku: Out (Physical discomfort).
  • Zambo Anguissa: Out (International duty – AFCON).
  • Billy Gilmour: Out (Groin surgery recovery).
Scott McTominay of SSC Napoli celebrates after scoring during the Serie A match between SSC Napoli and Empoli FC at Stadio Diego Armando Maradona Naples Italy on 14 April 2025.
(Photo by Franco Romano/NurPhoto via Getty Images)

Predicted Lineups

Inter Milan (3-5-2)

Sommer; Bisseck, Akanji, Bastoni; Darmian, Barella, Calhanoglu, Zielinski, Dimarco; Thuram, Lautaro Martinez.

Napoli (3-4-2-1)

Milinkovic-Savic; Di Lorenzo, Rrahmani, Sam Beukema; Juan Jesus, Lobotka, McTominay, Spinazzola; Politano, Elmas, Hojlund.


Betting Odds & Prediction

Data from 365Scores suggests a tight affair, though the home advantage gives Inter a significant edge.

  • Inter Milan Win: 1.77
  • Draw: 3.60
  • Napoli Win: 5.25

Our Prediction: While Napoli’s defense is world-class, the absence of Kevin De Bruyne and Romelu Lukaku leaves a void in their transition play. Chivu’s Inter are playing with immense confidence. We expect a 1-0 victory for Inter, with Marcus Thuram finding the net.


What to Watch For

  1. The Apprentice vs. The Master: Cristian Chivu has admitted he has “a lot to learn” from Conte, but his tactical flexibility this season has been Inter’s secret weapon.
  2. The McTominay Threat: Scott McTominay has a knack for scoring against the Nerazzurri, having netted in both of his previous meetings against them.
  3. Defensive Dominance: Inter’s defenders have already combined for 7 goals this season. Watch for Dimarco’s overlapping runs to stretch Napoli’s backline.

For real-time updates, live scores, and heat maps for this match, head over to 365Scores.